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KMID : 1134820110400070969
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Journal of the Korean Society of Food Science and Nutrition
2011 Volume.40 No. 7 p.969 ~ p.974
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Inhibitory Effect of Ecklonia cava Extracts against Lipase Activity and Stability Effect of Temperature and pH on Their Activity
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Jung Ji-Yeon
Kim Koth-Bong-Woo-Ri
Lee Chung-Jo
Kwak Ji-Hee
Kim Min-Ji
Kim Dong-Hyun
Sun Woo-Chan
Kim Tae-Wan
Ahn Dong-Hyun
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Abstract
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This study was performed to investigate the inhibitory activity of Ecklonia cava (EC) against lipase and the stability of this activity under various heat and pH conditions. As a result, EC ethanol extract showed lipase inhibitory activity of 59, 34 and 19% at concentrations of 5, 2.5 and 1 ㎎/㎖, whereas the water extract showed low inhibitory activity at all concentrations compared to that of the ethanol extracts. In a heat and pH stability test, the inhibitory activity of the EC ethanol extract increased with heat treatment at 121℃ for 15 min compared with the control and was stable in the pH range of 2~10. Therefore, the EC ethanol extract could be useful as a natural anti-obesity agent.
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KEYWORD
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Ecklonia cava, lipase inhibitor, ethanol extract
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